SYSUCC Sun Yat-sen University Cancer Center

OUR TOOLS


Deep-PLA
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Deep-PLA is a web server developed for understanding the reversible enzyme-specific lysine acetylation regulation for histone acetyltransferases (HATs) including CREBBP, EP300, HAT1, KAT2A, KAT2B, KAT5 and KAT8, and deacetylases (HDACs) including HDAC1, HDAC2, HDAC3, HDAC6, SIRT1, SIRT2, SIRT3, SIRT6, and SIRT7.
Deep learning based prediction of reversible HAT/HDAC-specific lysine acetylation
Briefings in Bioinformatics.
2019, bbz107.
doi: 10.1093/bib/bbz107.

DeepCalpain
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DeepCalpain is a web server based on deep learning to predict calpain-specific cleavage events. Given a protein or a set of proteins in FASTA format, it can predict the possible cleavage sites of two major types of calpain, including m-calpain and μ-calpain.
Precise prediction of calpain cleavage sites and their aberrance caused by mutations in cancer
Frontiers in Genetics.
2019 Aug 8, 10:715.
doi: 10.3389/fgene.2019.00715.

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

DeepGSH
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DeepGSH is a web server based on deep learning to predict S-glutathionylation sites. Given a protein or a set of proteins in FASTA format, it can predict the possible S-glutathionylation sites in proteins.
Deep learning based prediction of species-specific protein S-glutathionylation sites
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics.
2020 Jul, 1868(7):140422.
doi: 10.1016/j.bbapap.2020.140422.

prkC-PSP
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In this study, we manually curated the experimentally iden-tified substrates and phospho-rylation sites of prkC from the published literature, and developed a novel software of prkC-PSP (prkC-specific Phosphorylation Sites Prediction) for the prediction of prkC-specific phosphorylation sites.
Prediction of prkC-mediated protein serine/threonine phosphorylation sites for bacteria
PloS one.
2018 Oct 2, 13(10):e0203840.
doi: 10.1371/journal.pone.0203840.

Advances in experimental medicine and biology

cPhosBac
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In this study, we present a new predictor of cPhosBac to predict phosphorylation serine/threonine in bacteria proteins.
Prediction of serine/threonine phosphorylation sites in bacteria proteins
Advances in experimental medicine and biology.
2015, 827:275-85.
doi: 10.1007/978-94-017-9245-5_16.